Package: AbSolution Title: Interactive Feature-Based Analysis of AIRR-Seq Data Version: 1.0.2 Authors@R: c( person("Rodrigo", "García-Valiente", , "r.garciavaliente@amsterdamumc.nl", role = c("cre", "aut"), comment = c(ORCID = "0000-0003-0444-5587", email2 = "rodrigo.garcia.valiente+absolution@email.com")), person("Charisios", "Triantafyllou", , "charisios.triantafyllou@genyo.es", role = "aut", comment = c(ORCID = "0000-0002-0283-141X")), person("Antoine", "van Kampen", , "a.h.c.vankampen@amsterdamumc.nl", role = c("aut", "ths"), comment = c(ORCID = "0000-0003-1025-7232")) ) Description: An interactive framework for the exploration and analysis of adaptive immune receptor repertoire sequencing (AIRR-seq) data. It enables large-scale computation and integrated analysis of sequence-derived features, including physicochemical properties, amino acid descriptor sets, sequence motifs, compositional patterns, and somatic hypermutation metrics. The application supports multiscale analysis across sequences, clones, and repertoires, with interactive visualizations and statistical feature selection. 'AbSolution' also facilitates reproducible research by enabling structured export of data, code, parameters, and computational environments. See for more details. License: GPL (>= 3) URL: https://github.com/EDS-Bioinformatics-Laboratory/AbSolution, https://eds-bioinformatics-laboratory.github.io/AbSolution/ BugReports: https://github.com/EDS-Bioinformatics-Laboratory/AbSolution/issues Depends: R (>= 4.4.0) Imports: alakazam, attachment, benchmarkme, bigassertr, bigparallelr, bigstatsr, Biostrings, bs4Dash, callr, colourpicker, config (>= 0.3.2), dashboardthemes, data.table, dockerfiler, doParallel, dplyr, DT, foreach, fresh, fs, ggplot2, golem (>= 0.4.1), grDevices, htmlwidgets, IRanges, knitr, parallel, Peptides, plotly, pwalign, reactable, rlang, rmarkdown, seqinr, shiny (>= 1.7.4), shinycssloaders, shinyFiles, shinyjs, shinymanager, shinymeta, shinythemes, shinyWidgets, sortable, stats, stringdist, stringr, sunburstR, tools, umap, upsetjs, utils, viridis, xfun Suggests: testthat (>= 3.0.0) VignetteBuilder: knitr Additional_repositories: https://bioconductor.org/packages/release/bioc Config/testthat/edition: 3 Encoding: UTF-8 Language: en-US RoxygenNote: 7.3.3 Config/pak/sysreqs: cmake git libglpk-dev make libbz2-dev libgit2-dev libicu-dev liblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev python3 libx11-dev xz-utils zlib1g-dev Repository: https://eds-bioinformatics-laboratory.r-universe.dev Date/Publication: 2026-09-25 11:29:50 UTC RemoteUrl: https://github.com/eds-bioinformatics-laboratory/absolution RemoteRef: HEAD RemoteSha: 1e4f9c4485ea73042124b62949c6f8234fd45bb1 NeedsCompilation: no Packaged: 2026-10-25 11:59:13 UTC; root Author: Rodrigo García-Valiente [cre, aut] (ORCID: , email2: rodrigo.garcia.valiente+absolution@email.com), Charisios Triantafyllou [aut] (ORCID: ), Antoine van Kampen [aut, ths] (ORCID: ) Maintainer: Rodrigo García-Valiente